Endocrine Abstracts

Introduction/Aim: The diagnosis and management of hypothyroidism in pregnancy is a domain of shifting paradigms, with changes in guidelines, which may have led clinicians to confusion or angst (Endocrine Today; October 2019). Since sentiment analysis (SA) of medical texts can be implemented (Artificial Intelligence in Medicine 2015; 64: 17–27) we sought to use SA regarding this clinical issue.Materials/Methods: We collected the English language abst...

Introduction: Metastases to the thyroid are rare (1.4–3% of malignant solid tumors). When present, metastatic cancers mimic the ultrasound image of the thyroid parenchyma, hindering diagnosis. Breast cancer rarely metastasizes to the thyroid.Case: A 61-year-old woman was referred for goiterin the context of post-surgery evaluation for breast cancer. Thyrotropin (1.14 mIU/l), calcitonin (0.5 pg/ml) and parathyroidhormone (54 pg/ml) levels were norma...

Introduction: Lactation is a period of particular importance regarding the management of glycemia in women with Diabetes Mellitus type 1 (DM1), the aim being to prevent hypoglycemia during breastfeeding. The purpose of this study was to investigate the variation of insulin requirements during lactation in comparison with pre-pregnancy levels in women with DM1 and to find potential correlation factors.Materials-methods: We conducted a retrospective case f...

Introduction: Internet users perform health information-seeking searches triggered by personal symptoms or diseases. Such searches may provide information - albeit indirectly - on disease patterns and epidemiology (PLoS One. 2014, 9:e109583, PNAS 2016; 113:6689-94). It was recently reported that in Asia (more particularly in Taiwan), online searches for obesity and diet (indirectly reflecting corresponding health-seeking behaviors) at times of financial crisis (recession) were...

Introduction: Cynicism (or cynical distrust) is described as a state of mind and belief that most people are selfish. Cynicism is an attitude characterized by general distrust of the motives of others, and some experts describe it as a form of chronic anger. Negative emotions, especially cynicism, may be harmful to physical health.Aim: The assessment of cynicism in pregnant women with common endocrine diseases.Subjects – Metho...

Introduction: Betamethasone (BM) is widely used in pregnancy. Its diabetogenic potential is known, and in combination with placental insulin resistance in pregnancy, leads to a transient increase in glycemia. Our aim was to study the changes in glycemia in women with singleton pregnancies and pre-existing diabetes mellitus, under insulin therapy, after administration of BM for obstetric causes.Materials and methods: We closely monitored and assessed the ...

Introduction: Prolactinomas are rarely found in adolescents under 15 (incidence 0.1/1.000.000). They account for 50% of all types of pituitary adenomas in childhood and adolescence (2% of intracranial tumors). The mean time from onset of symptoms to diagnosis is 2.4 years on average for girls. In cases of macroadenomas, TSH and GH deficiency may coexist. The gold standard primary therapy is dopamine agonists. In case of non-response, or the presence of large prolactinomas with...

Introduction: Researchers argue that increased morbidity is noted in pregnant women during the current COVID-19 pandemic. Reports indicate that the pandemic has led to disruptions in care of persons with diabetes. Glycated hemoglobin A1c (A1c) is not sufficient in screening for gestational diabetes mellitus (GDM) but may be of use in monitoring glycemia in GDM. To the best of our knowledge no studies honed on late pregnancy glycemia (via A1c), as a surrogate of the access/qual...

Introduction: The role of thyroid hormones is important in testicular development and function (involvement in Sertoli cell proliferation and functional maturation control and postnatally in Leydig cell differentiation and steroidogenesis). Additionally, thyroid hormone receptors are found in testicular cells throughout development and in adulthood. Our aim was to study thyroid hormone effects on testicular function.Materials and methods: We retrospectiv...

Introduction: Exposure to air pollution and in particular to nitrogen dioxide (NO2) or particulate pollutants less than 2.5 µm (PM2.5) or 10 µm (PM10) in diameter has been linked to thyroid (dys)function in pregnant women. The environmental degradation that has occurred in recent years in the region of Athens led us to a local study of air pollution against thyroid function in pregnant women in Athens. We hypothesized that there may be a dose-effect relati...